MCDB_1A_MT_1_A_Green_2010

MCDB_1A_MT_1_A_Green_2010 - Name _ TA _ MCDB 1A Midterm...

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Name _________________________ TA ________________________ MCDB 1A Midterm Examination I October 19, 2010 Scantron Instructions: 1. Use a #2 pencil to complete the form. 2. Write your name and fill in the appropriate bubbles. 3. Write your perm. number in the ID number box and fill in the bubbles. 4. Write the color of your test in the space underneath the ID number box. 5. Fill in the entire rectangle of the answer you choose. If you erase, erase completely STAY CALM, CONCENTRATE AND GOOD LUCK GENETIC CODE, AND METABOLIC PATHWAYS DIAGRAMS AT END OF EXAM READ ALL QUESTIONS THOROUGHLY----IN ALL CASES, PICK THE BEST ANSWER 33 QUESTIONS - 3 POINTS EACH Test Color - 1 Point 1. Protein structure can be described in terms of primary, secondary, tertiary and quaternary structure. How many of these levels of structure can involve covalent bonds? A. 1 B. 0 C. 4 D. 3 E. 2 2. Which strand of DNA in the replication fork drawn below is going to be the template for the "leading strand"? A. both will be leading strands B. neither strand will be a leading strand C. right strand D. left strand E. more information is required to answer the question MCDB 1A MT 1 A Green (2) Version: 2 Page: 1
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3. The overall reaction for the metabolic breakdown of glucose is: C 6 H 12 O 6 +6 O 2 -------> 6CO 2 + 6H 2 O In what stage of metabolism are most of the carbon atoms from glucose oxidized? A. the TCA cycle B. Glycolysis C. electron transport/oxidative phosphorylation D. the "pre-entry reaction" (pyruvate to acetyl CoA) E. none is a correct answer because the carbon atoms are oxidized equally in all stages of metabolism. 4. If the reaction A + B -------> C + D has a ! G = -9 kcal/mole, what would you expect about the reaction? A. it will go forward very slowly B. it will go forward very quickly C. more information is required in order to know how fast it will go 5. Is this the correct chemistry for peptide bond formation? A. Yes B. No 6. Consider the following transcription bubble. If the template strand to be transcribed is the upper strand, will RNA polymerase move right to left, or left to right? A. Right to left B. Left to right C. insufficient information to answer the question MCDB 1A MT 1 A Green (2) Version: 2 Page: 2
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7. Imagine that you are working on a transmembrane protein called Miso, which when mutated causes an inherited human disease. You discover that people with the disease have an extra amino acid in the transmembrane domain of their Miso. Everything else in the primary structure of Miso is normal. At some point way back in history, there must have been an event that caused this error. The most likely molecular explanation
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This note was uploaded on 02/13/2011 for the course MCDB 1a taught by Professor Feinstein during the Fall '08 term at UCSB.

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MCDB_1A_MT_1_A_Green_2010 - Name _ TA _ MCDB 1A Midterm...

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