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MCB 32L Lab Report #8

MCB 32L Lab Report #8 - Jae Shin(Clarice Kim Janice Chow...

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Jae Shin (Clarice Kim, Janice Chow, Regine Leger) 11/16/10 Wendy Ingram Lab Report #8 Lab 8: Renal Control of Body Fluids, Electrolytes and pH I. Introduction Background: In this lab, we will examine the human kidney functions and its ability to maintain homeostasis. A human being has two kidneys and each kidney is made up of approximately a million nephrons that maintain proper body fluid volume and composition. The nephron itself is divided in to five sections that each contribute to filtration of bodily fluids – Bowman’s capsule, PCT, loop of Henle, DCT, and the collecting duct. The kidney filters over 180 liters of blood every day. The amount that’s been filtered plus the amount secreted minus the reabsorbed equals what’s left in the kidney which ultimately excretes out of the body as urine. The body can protect itself from plasma pH changes by two ways: secrete H+ from the kidney tubules or the excess H+ combines with the bicarbonate ion and drive the below reaction left. CO2 + H2O H2CO3 H+ + HCO3- ADH, anti-diuretic hormone, controls the permeability of the DCT and CD to water. Once released, water reabsorption is increased and as a result, less water is excreted from the body. Sodium reabsorption is also under the control of a hormone called aldosterone, which is secreted from the adrenal gland. Aldosterone increases Na+ reabsorption via DCT. Hypothesis: For my hypothesis, I expect difference in sodium concentration and Osmolarity between the water control group and the NaCl tablet group. I do not predict much difference for volume because the liquid absorbed is relatively the same for the subjects. The pH should also not vary between the two groups because if there
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