lecture 18 - Update Problem set grading- scores are final -...

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1 Update Problem set grading- scores are final - no chance for regrade Essays are going to take long time to grade –I’m not giving these back – I will post the score MC scores will be ready next week Exam Nov 19 4pm-5:15 room 6210 soc sci Tuesday Nov 16 – Info on exam Go over answers to problem set MC and essay
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2 Lecture 15 Vaccines How can we prevent infectious disease by providing “immunity” before contact with the pathogen?
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3 DPT T etanus toxoid, d iphteria toxoid, P ertussis toxins chemically treated How does this vaccine maintain protective anti- tetanus antibody levels Boosters –tetanus toxoid only Adjuvants Pertussis (killed whole bacteria) -controversy over “adverse effects” No vaccine - Increased incidence of whooping cough and deaths New vaccine = acellular (DTaP) Subunits May need boosters
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4 Polio vaccine Inactivated (Salk) Good immunity-mainly IgG antibody Oral-live attenuated (Sabin) Better immunity (mucosal, IgGab +CMI) But-Shed virus – can replicate in host Recently, in this country, due to lack of virus in population, more cases of polio caused by vaccine Now require the inactivated vaccine
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5 Variation in some pathogens Serotypes of pneumococcus Over 90 different polysaccharide capsules Influenza virus Important epitopes for neutralization change over time Virus replicates in different hosts and exchange genes with other influenza viruses that “mix ” eptitopes creating new variants from year to year
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6 Vaccines face public scrutiny Medical treatment in developed world is very good Vaccines are given when individuals are
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This note was uploaded on 02/14/2011 for the course ORGANIC CH 341 taught by Professor Idk during the Spring '11 term at Wisconsin.

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lecture 18 - Update Problem set grading- scores are final -...

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