SNBAL 3 1. Multiple Sclerosis is an autoimmune disease that affects the central nervous system. MS causes inflammation of neurons, demyelization and breakdown of axons. Both environmental and genetic factors are thought to play a role in the acquisition of MS. Most patients (80-85%) are diagnosed with relapsing-remitting MS (RRMS), where the disease is sometimes active (causing neurological dysfunction) and sometimes in remission (allowing relatively normal function). A small group of patients (10-15%) have a more degenerative form of MS, which progresses over time, called primary progressive MS. Over 50% of the patients with relapsing-remitting MS experience neurological breakdown within 10 years of being diagnosed, essentially experiencing a hybrid of the two types of MS. This hybrid condition is called secondary progressive MS. 2.
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