30 - MCB 142 Professor Georjana Barnes 11/5/07 Lecture 30...

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Lecture 30 ASUC Lecture Notes Online (formerly Black Lightning) is the only authorized note-taking service at UC Berkeley. Please do not share, copy or illegally distribute these notes. Our non-profit, student-run program depends on your individual subscription for its continued existence. These notes are copyrighted by the University of California and are for your personal use only. Sharing or copying these notes is illegal and could end note taking for this course On the board: Exam rooms 10 Evans: Philip, Meghan, Adam 155 Dwinelle: other GSIs DSP 35 Evans ANNOUNCEMENTS So what we’re passing out now is the evaluation of Professor Rokhsar. ( Evaluations ). First of all, I’m Georjana Barnes, and what I plan to do today is review some essential concepts that you will all know and you should all know. What I’m going to present today should be no shock to anyone but it is essential material for anyone who’s taking a genetics class. These are really important points; if you know nothing about genetics, I want you to know these points. But first, I want you guys to acknowledge your GSIs ( applause ). It’s clear from evaluations that you guys filled out that your GSIs are doing a great job for you. And it’s not an easy job that they have since they have their own careers and studies to handle as well. Next, the rooms for the second exam are the same ones you went to for the first exam, ( refers to board ). Finally, my office hours will be Wednesdays 12:30 to 2:30 in 608 Barker Hall. INTRODUCTION So I’ve been sitting in on all of Professor Slatkin’s lectures and many of Professor Rokhsar’s lectures so what I want to do today is the introduction to what we’re going to be covering in the next 5 weeks which has to do with using genetics analysis and genetics to understand the world of single-celled and multi-celled organisms at the molecular level. So it’s a bit of reviewing what you went over with Professor Slatkin when you were learning about mutant phenotypes, but there you didn’t have to understand what was going on at the molecular level. You were just looking at peas – yellow, wrinkled, etc – and categorizing them and trying to understand what you were seeing and seeing how they were inherited from generation to generation. Then with Professor Rokhsar, you went into more detail of the mechanics of processes like transcription, translation, and also into some genomic analysis (such as how you use mutant alleles to construct maps of genomes.) But what we’re going to do in the next five weeks is understand what’s going on when you have a mutation; maybe you’re making a protein and they have a certain phenotype under certain conditions and not others. In the next 5 weeks, we’re going to let genetics clarify our understanding of the genetic world. So we’re going to do prokaryotic gene
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30 - MCB 142 Professor Georjana Barnes 11/5/07 Lecture 30...

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