Z331 Fall 2010 Ecampus Week 5 Muscle Microanatomy II Posted

Z331 Fall 2010 Ecampus Week 5 Muscle Microanatomy II Posted...

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Week 5: Lecture 2: Chapter 10 –   Muscular Tissue: Microanatomy II:  Myofilaments
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Organization of Skeletal Muscle Fibers: Myofibrils Made up of  bundles of  myofilaments  (cytoskeletal  elements) Myofilaments are  responsible for  muscle contraction  fig. 10.2, 306
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Types of Myofilaments  Thin filaments:  made of several  proteins Thick filaments:  made of two  proteins fig. 10.3, 308
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A Thin Filament Figure 10.3, 308 & 10.5, 310
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4 Thin Filament Proteins 1. Actin – contractile 2. Tropomyosin – regulatory 3. Troponin – regulatory 4. Structural proteins Martini, Figure 10–7, 291 Figure 10.5, 310
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A Thick Filament Contain twisted myosin subunits (contractile)  Contain titin (structural) strands that recoil after  stretching Titin: C 132983 H 211861 N 36149 O 40883 S 693 Figure 10.5, 310 Figure 10.3, 308 & 10.5, 310
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The Myosin Molecule Seely, 6 th  ed, fig 9.4 Martini, Figure 10–7, 291 Fig 10.7, 313
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Z331 Fall 2010 Ecampus Week 5 Muscle Microanatomy II Posted...

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