Lecture 1 Homeostasis

Lecture 1 Homeostasis - Lecture 1 Robustness, Stability and...

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Lecture 1 Robustness, Stability and Homeostasis
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Mechanisms that contribute to stability are generally described by analogy to engineering concepts. 1. Control theory, feedback loops, homeostasis 2. Robust networks
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Traditional Chinese Medicine The human body is a small universe with a set of interconnected systems that usually work in balance to maintain the healthy function of the human body. The balance of yin and yang is considered important to maintain health.
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Claude Bernard "The constancy of the internal environment is the condition for a free and independent life“ - 1856
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William Cannon Homeostasis (1932): homeo – similar + stasis – condition - maintaining a similar condition
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William Cannon Homeostasis (1932): 1. Constancy in an open system, requires mechanisms that act to maintain this constancy. e.g. steady states for glucose concentrations, body temperature and acid-base balance. 1. Steady-state conditions require that any tendency toward change automatically meets with factors that resist change.
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Lecture 1 Homeostasis - Lecture 1 Robustness, Stability and...

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