L10W10_MIC105_BAEContrasts

L10W10_MIC105_BAEContrasts - Lecture 9 Implications of the...

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Lecture 9: Implications of the rooting of the Big Tree Thursday, January 28, 2010
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Metabolic diversity Bacteria: very diverse Respiration (O 2 & anaerobic), fermentation, photosynthesis, rhodopsins, autotrophy, N 2 fixation, denitrification, sulfate reduction, hyperthermophiles Archaea: very diverse Respiration (O 2 & anaerobic), fermentation, rhodopsins, autotrophy, methanogenesis, N 2 fixation, denitrification, sulfate reduction, hyperthermophiles Eukaryotes: restricted Respiration (O 2 ), fermentation, photosynthesis * Thursday, January 28, 2010
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Pathogenicity Bacteria: pathogens in some lineages e.g. Proteobacteria, Gram Positives, Spirochetes, cyanobacteria (toxins), Chlamydiae, Bacteroides Archaea: no known pathogens to date! Eukaryotes: most lineages have some pathogenic members * Thursday, January 28, 2010
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Ribosomes and protein translation Bacteria and Archaea: 70S Ribosome (30S + 50S) RNA sizes 16S, 23S, 5S Eukaryotes: 80S Ribosome (40S + 60S) RNA sizes 18S, 28S, 5.8S, 5S 16S = 18S = small subunit rRNA (ssu rRNA) -Giardia 23S = 28S = large subunit rRNA (lsu rRNA) Bacteria : start codon calls for formylmethionine Archaea and Eukaryotes : initiator t-RNA carries unmodified methionine * Thursday, January 28, 2010
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Archaeal lipids in the cytoplasmic membrane Bacteria, Eukarya: ester linkages, typically linear fatty acid side chains Archaea: ether linkages, branched hydrocarbon side chains Exceptions: ether linkages in a few sulfate reducing bacteria and Propionibacterium species * Thursday, January 28, 2010
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Isoprene * Thursday, January 28, 2010
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