Student%20Lecture%2017%20%28Dallas%20Bed%20Rest%20Study%29

Student%20Lecture%2017%20%28Dallas%20Bed%20Rest%20Study%29...

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Unformatted text preview: Lecture 17 Dallas Bed Rest and Training Study Dallas Thursday 3­11­10 Announcements – Extra Credit Outline Outline Grant Assignment #3 (Emailed before class) Discussion 3/24, Armstrong 1109, 3:30 – 30 Year Follow up to the Dallas Bed Rest and Training Study Test Dallas Bed Rest and Training Study Dallas 1966 Investigators – – – – – – Bengt Saltin Gunnar Blomqvist Jere Mitchell Robert L. Johnson Kern Wildenthal Carleton B. Chapman http://users.hal­pc.org/~ghill/1966.html Mitchell & Chapman http://users.hal­pc.org/~ghill/1966.html 1966 Research Team Subjects Subjects (n=5) – – – – – Bill Bowman Kazmer Laszlo Gregg Hill James Hulsley Leo Luebbenhusen Training status – 2 trained – 3 untrained http://users.hal­pc.org/~ghill/1966.html 1966 Subjects Protocol Protocol Baseline measurements Three weeks of – Post bed rest measurements http://users.hal­pc.org/~ghill/1966.html Eight weeks 3 weeks Bed Rest – Post aerobic training measurements http://users.hal­pc.org/~ghill/1966.html 8 weeks aerobic training Measurements Measurements http://users.hal­pc.org/~ghill/1966.html http://users.hal­pc.org/~ghill/1966.html http://users.hal­pc.org/~ghill/1966.html http://users.hal­pc.org/~ghill/1966.html Measurements Measurements http://users.hal­pc.org/~ghill/1966.html http://users.hal­pc.org/~ghill/1966.html http://users.hal­pc.org/~ghill/1966.html http://users.hal­pc.org/~ghill/1966.html Results Bed Rest Results Results Aerobic Exercise Training Results Dallas Bed Rest and Training Study Dallas 1996 Investigators – – – – – – – Bengt Saltin Gunnar Blomqvist Jere Mitchell Darren McGuire Peter Snell Ben Levine J.W. Williamson http://users.hal­pc.org/~ghill/1966.html Saltin, Blomqvist & Levine http://users.hal­pc.org/~ghill/1966.html McGuire, Hill, Luebbenhusen, Hulsey & Mitchell Protocol Protocol Baseline measurements Chronic endurance exercise training – – http://users.hal­pc.org/~ghill/1966.html Gregg Hill Training with Dogs Measurements Measurements Hydrostatic weighing for body composition Graded exercise testing for cardiovascular variables Effects of Aging on Baseline Measurements Measurements Weight % Body Fat MAP HR VO2 CO SV A­VO2 diff Heart volume Effects of aging on blood Effects Cholesterol Triglycerides Hematocrit Hemoglobin Confirmation of VO2max Confirmation Criteria of VO2max – Respiratory exchange ratio ≥ 1.15 – HR in last stage ± 10 beats•min­1 of HRmax – Plateau in VO2 with increasing work rate – Blood lactate > 8mmole/liter Effects of Estimated Daily Activity on VO2max on Fig. 1 Effects of Aging on VO2max Effects VO2max decreased by over 30 yrs. Fig. 2 Fig. 3 Effects of Aging on Cardiac Output Effects Cardiac output Heart rate Stroke volume – – Fig. 4 – Fig. 5 Fig. 6 Effects of Aging on A-VO2 diff Effects A­VO2 difference – Fig. 7 Effects of Aerobic Exercise on Aging Aging Endurance Exercise Training 1966 vs. 1996 1966 Fig. 1 Effects of Aerobic Exercise Training on Baseline Characteristics Effects of Aerobic Exercise Training on VO2max on VO2max increased with aerobic exercise training by: – Fig. 3 Effects of Aerobic Exercise Training on Cardiac Output Max on Cardiac Output Stroke Volume Heart Rate – – Fig. 5 – Fig. 6 Fig. 7 Effects of Aerobic Exercise Training on Total Peripheral Resistance Total Total peripheral resistance – Fig. 9 Effects of Aerobic Exercise Training on A-VO2 difference on A­VO2 difference – Fig. 8 ...
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