Unformatted text preview: C <’ Regulation of Catalytic Activity (prilmlglwg’46
F25 mm hm much. wag lo Ia. < .
Glutamate + NH3‘_—‘“‘>G|utam|ne mm) a
Wﬂ‘émnnéb ”4:153?“ galwm] 12 ATP activ 12 AMP adenylation deadenylation 12PPi
12AMP inactive GS is composed of 12 identical subunits, each of which binds an AMP
1 AMP -> inhibits GS activity 1l12 GS = glutamine synthase UTase = uridyl transferase CW W“ MM” PII = central regulatory protein ATase = adenyl transferase (Mull) may w bummed) URenz = uridyl-removing enzyme (mm; uwz WAR} ...
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- Spring '08