Unformatted text preview: ,/‘\ DNA Replication
Genes VIII: ch 13. & Ch.14. Only Will use portions General Background
1953 - Watson Crick Model of how DNA replicates. Heredity 1954 - A. Kornberg - Isolation of DNA polymerase I 1958 — Meselsohn and Stahl: Showed DNA replicates semi—
conservatively. 1 of the 2 strands conserved in next generation 15N and 14N isotopes: \.
LH 1950’s- 1960’s Genetic approaches E. coli genome is circular a Mapping genes implied a circle 1960 - Jacob & Monod proposed one origin, bidirectional or
unidirectional replication? ...
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- Fall '09