Biopsychology Exam 4-part 2

Biopsychology Exam 4-part 2 - Biopsychology Exam 4 Lecture...

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Biopsychology Exam 4 Lecture 19- Pyschopathology: Pyschopathologies affect 100s of millions of people worldwide (1/3 of Americans report psychiatric disorders BIOLOGICAL PERSPECTIVE FOR PSYCHIARTY: grew in early 20 th century when many patients with brains damaged by syphilis, in mental hospitals, with delusions; antibiotics that killed the bacteria causing syphilis eliminated “syphilic psychosis” mental disorders can have a biological cause SCHIZOPHRENIA- 2 main types: positive and negative; 1-2% people (across cultures) have it (about 2.2 million Americas); appears in adolescence and young adults; extremely complex disorder o “public disorder” – many people who have it end up on the streets (consuming a disproportionate amount of community health resources) o POSITIVE SYMPTOMS: abnormal behavioral states that have been gained (something new); delusions (false beliefs; usually highly personalized), excited motor behavior and hallucinations (hearing voices that aren’t there; type of delusion) o NEGATIVE SYMPTOMS: abnormalities that result in a loss of a normal function (ex: slow thoughts and speech); emotional/social withdrawal (emotions= extremely flat; they just sit and stare into nothing), blunted affect/ emotions (blunted expression of emotions), and impoverished thought o Predisposition of genetic component and contribution from environment and development SCHIZOPHRENIA IS INHERITED—but not a simple genetic determinism; multiple genes involved (genes important to schizophrenia are located on at least 15 or 23 chromosomes); genetic nature is extremely complicated and poorly understood identical twins (monozygotic)=came from same egg (same genome); 48% chance of getting schizophrenia if twin has it (the more genetically related a person is to schizophrenia, the greater chance they have of getting it) fraternal twins (dizygotic)=2 different eggs—half their genes in common (like non-twin siblings); 17% chance of getting disease if other sibling has it **if both twins have the trait=CONCORDANT
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o 50% of identical twins are concordant for schizophrenia, also show similar limbic structure (hippocampus and amygdala) **if only one twin has the train=DISCORDANT o if t wins are discordant they usually vary in other traits too (ex: differences in motor coordination); they show differences in their limbic system; low blood flow in frontal cortex only seen in twin with schizophrenia patients with schizophrenia: greater difficulty making smooth-pursuit movements with eyes than non-schizophrenics (people with schizophrenia= jerky eye movements) o People with schizophrenia that were adopted: biological parents are much more likely to have disorder than adoptive parents o People with disorder have enlarged lateral ventricles enlarged NOT related to length of illness; patients with larger ventricles (more severe damage) don't respond to medication as well o Brain abnormalities: **lmbic structures (amygdala and hippocampus)=near ventricles, resulting in
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This note was uploaded on 02/18/2011 for the course PSYCH 230 taught by Professor Unkown during the Winter '08 term at University of Michigan.

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Biopsychology Exam 4-part 2 - Biopsychology Exam 4 Lecture...

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