8. Integration 2010

8. Integration 2010 - 1. No proteins 2. HCO 3- 3. H 2 PO 4-...

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Unformatted text preview: 1. No proteins 2. HCO 3- 3. H 2 PO 4- 1. Proteins 2. HCO 3- 3. H 2 PO 4- CA CA 1. Proteins 2. HCO 3- 3. H 2 PO 4- Plasma 1. Hb (protein) 2. HCO 3- 3. H 2 PO 4- CA RBC Tissue Blood (2 compartments) ISS 5. Integration 1 Proximal tubule + thick ascending limb Lumen of tubule ISS 5. Integration 2 Lumen of blood vessel PTC Cl- HCO 3- 2K+ 3Na+ Na + H + CO 2 + H 2 O H 2 CO 3 H + + HCO 3- H 2 CO 3 H + CA HCO 3- + CA Na + 3HCO 3- CO 2 + H 2 O Cl- HCO 3- 2K+ 3Na+ K + H + CO 2 + H 2 O H 2 CO 3 H + + HCO 3- CO 2 + H 2 O H 2 CO 3 H + CA HCO 3- + CA Collecting duct H + H + 2K+ 3Na+ Cl- HCO 3- CO 2 + H 2 O H 2 CO 3 H + + HCO 3- CA Formation of new HCO 3- Cl- 5. Integration 3 HCO 3- 2K+ 3Na+ CO 2 + H 2 O H 2 CO 3 H + + HCO 3- H + + CA Collecting duct H + Buffer H-Buffer Proximal tubule and collecting duct - role of ammonia HCO 3- 2K+ 3Na+ Na + NH 4 + Glutamine PT H + 2K+ 3Na+ H + CO 2 + H 2 O H 2 CO 3 H + + HCO 3- CA Na + H + NH 4 + NH 3 H + NH 3 NH 4 + + + 2 HCO 3- Cl- NH 4 + + NH 3 CD 7.0 7.1 7.2 7.3 7.4 7.5 7.6 7.7 7.8 7.9 5 15 25 35 45 55 PCO 2 =60mmHg PCO 2 =40mmHg PCO 2 =20mmHg HCO 3- =normal HCO 3- =+10mM/L HCO 3- =+5mM/L HCO 3- = -5mM/L pH H C O 3- ( m M / L ) 5. Integration 4 7.0 7.1 7.2 7.3 7.4 7.5 7.6 7.7 7.8 7.9 5 15 25 35 45 55 PCO 2 =60mmHg PCO 2 =40mmHg PCO 2 =20mmHg HCO 3- =normal HCO 3- =+10mM/L HCO 3- =+5mM/L HCO 3- = -5mM/L pH H C O 3- ( m M / L ) 5. Integration 5 7.0 7.1 7.2 7.3 7.4 7.5 7.6 7.7 7.8 7.9 5 15 25 35 45 55 PCO 2 =60mmHg PCO 2 =40mmHg PCO 2 =20mmHg HCO 3- =normal HCO 3- =+10mM/L HCO 3- =+5mM/L HCO 3- = -5mM/L pH H C O 3- ( m M / L ) 5. Integration 6 7.0 7.1 7.2 7.3 7.4 7.5 7.6 7.7 7.8 7.9 5 15 25 35 45 55 PCO 2 =60mmHg PCO 2 =40mmHg PCO 2 =20mmHg HCO 3- =normal HCO 3- =+10mM/L HCO 3- =+5mM/L HCO 3- = -5mM/L pH H C O 3- ( m M / L ) 5. Integration 7 REGULATION OF [H...
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This note was uploaded on 12/13/2010 for the course HK 3940 taught by Professor Murrant during the Fall '10 term at University of Guelph.

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8. Integration 2010 - 1. No proteins 2. HCO 3- 3. H 2 PO 4-...

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