1 174 3rd icyc 2010 universiti sains malaysia nat p9

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Unformatted text preview: ; Molecular Biology (ISB), Faculty of Science, University Malaya, Kuala Lumpur, Malaysia 3 Cancer Research Initiative Foundation, Subang Jaya, Selangor, Malaysia 4 Department of Ecology and Biodiversity, (ISB), Faculty of Science, University Malaya, Kuala Lumpur, Malaysia 5 Department of Chemical Science, Faculty of Science and Technology, University Malaysia Terengganu, Mengabang Telipot, 21030, Kuala Terengganu, Malaysia E-mail: [email protected] Nine natural compounds, Stigmasterol 1, β-sitosterol 2, 1’S-1’-acetoxychavicol acetate 3, trans-pcoumaryl diacetate 4, 1’S-1’-acetoxyeugenol acetate 5, 1’S-1’-hydroxychavicol acetate 6, phydroxycinnamyl acetate 7, p- hydroxycinnamaldehyde 8 and p-hydroxybenzaldehyde 9 were isolated from the rhizomes of Alpinia conchigera Griff. The structures were established by their NMR spectral data and by comparison of these data those reported in the literature. These six phenylpropanoid compounds (compound 3-8) were tested to MTT cell viability assays to describe the cytotoxic and apoptotic properties on human breast cancer cells (MCF7). 1 175 23rd-25th June 2010 3rd ICYC 2010 Universiti Sains Malaysia NAT-P10 ANTIOXIDANT ACTIVITY, TOTAL PHENOLIC CONTENTS AND TOXICITY OF LEAVES EXTRACTS OF HIBISCUS ROSA-SINENSIS LINN. 1 Lee Ye San, Boey Peng Lim and Dafaalla M.H. Ali 1 2 2 School of Chemical Sciences, Universiti Sains Malaysia, 11800 Pulau Pinang, Malaysia Department of Chemistry, College of Science, Sudan University of Science and Technology, P. O. Box 407 Khartoum, Sudan E-mail: [email protected] 1 Hibiscus rosa-sinensis is widely used in traditional medicine of Southeast Asia, China and India as laxative, in cough treatment, bronchial catarrh, diarrhoea and fertility control. Recent studies reported that the leaves and flowers exhibit hair growth promoting properties. The last application led us to carry out this study. Fresh and dry leaves were successively extracted with petroleum ether, ethyl acetate and ethanol. Sol...
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