130 3rd icyc 2010 universiti sains malaysia ino 16

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: ds namely: (1-(3’-aminomethyl-1’(H)-1’,2’,4’-triazole)-3(1’(H)1’,2’.4’-triazole-3’-yl)iminoisatin (LI) and 1-morpholinomethyl-3-(1’(H)-1’,2’,4’-triazolyl)iminoisatin (LII) were prepared by condensation reaction of the new Schiff base 3 -(1’(H)-1’,2’,4’-triazole-3’yl)iminoisatin (SBH) (0.01 mole) with formaldehyde and 3-amino-1,2,4-triazole (3-At) or morpholine respectively (0.01 mole each) .Structures were characterized by H NMR, CHN analyses, mass spectra and IR spectra. Metal complexes were synthesized by heating each ligand (0.02 mole) with metal salts of Mn(II), Co(II), Ni(II), Cu(II), Zn(II), Pd(II), Cd(II), Pt(IV), and Ir(III) ions (0.01 mole) in ethanol or ethanol/acetone mixture (1:1 v/v).The following formula of LI complexes were obtained: [Mn2(LI)3Cl2].2H2O; [CoLICl2].H2O; [Ni(LI)2]Cl2.H2O; [Cu2(LI)2(H2O)2]Cl2.2H2O; [ZnLICl]Cl.0.5C2H5OH; [IrLICl2]Cl; [PtLICl2]Cl2.H2O; and [Cd(LI)2(OAc)2].2H2O (C1-C8). Complexes of LII gave the formula: [Mn(LII)2]Cl2.2H2O; CoLII(NO3)]NO3.0.5H2O; [NiLII(NO3)2]0.5C2H5OH; [Cu2(LII)Cl2(H2O)2]2Cl2; Zn(LII)2OAc]OAc.0.5H2O; [PdLIICl]Cl.0.5C2H5OH; [PtLII]Cl4.1.5H2O(C9-C15). Structures of complexes were elucidated depending on CHN analysis, thermal analyses, atomic absorption spectroscopy, IR, UV -visible spectra, magnetic moments and conductivity measurements. All complexes were of octahedral geometry except the Palladium(II) complexes as they acquired square planar geometry. The two ligands and some selected metal complexes showed various antibacterial and cytotoxic ac tivities. INO-O17 SYNTHESIS AND FLUORESCENCE PROPERTIES OF COPPER (II) COMPLEXES OF ALKYL AND ARYL PYRIMIDINE DERIVATIVES 1 Edura Badaruddin, Zaharah Aiyub and Zanariah Abdullah 2 2 1 Chemistry Division, Centre for Foundation Studies In Science, University of Malaya, 50603 Kuala Lumpur, Malaysia 2 Department of Chemistry, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia E-mail: edura@um.edu.my 2-Chloropyrimidine, which was obtained commercially, was used as the precursor for the preparation of 2-N-ethylaminopyrimidine and 2-N-anilinopyrimidine. The ligands were then used as specific binder towards copper (II) metal ion in a 1:2 ratio (metal:ligand) to give their respective complexes. The structures of the ligands and complexes were confirmed by spe...
View Full Document

This note was uploaded on 02/17/2011 for the course CHEMISTRY 101 taught by Professor Csr during the Spring '11 term at University of Louisville.

Ask a homework question - tutors are online