9 mg g at 320 k the pseudo first order pseudo second

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Unformatted text preview: was found to be spontaneous and endothermic in nature. Desorption study was carried out at different concentrations of HCl and NaOH, more than 75 % of humic acid could be desorbed from the CCB beads using 1.0 M NaOH. Infrared spectra were used to elucidate the mechanism of humic acid adsorption onto CCB beads. The equili brium parameter (RL) indicated that the adsorption of humic acid onto CCB beads was favourable. ANA-P7 FIRST ORDER ULTRAVIOLET DERIVATIVE SPECTROPHOTOMETRY FOR DETERMINATION OF RESERPINE IN ANTIHYPERTENSION TABLET Wulan Tri Wahyuni, M. Rafi, Latifah K. Darusman, Elly Suradikusumah and Rizna Azrianiningsari Department of Chemistry, Faculty of Mathematic and Science, Bogor Agricultural University, Agatis Road IPB Darmaga, Indonesia E-mail: wulantriws@gmail.com Reserpine is an alkaloid derived from the roots of serpentwoods (Rauwolfia serpentina), which has been used for antihypertention and tranquilizer drugs. A new ultraviolet derivative spectrophotometry (UVDS) method has been developed for determination of reserpine in antihypertension tablet. Thi s method has been proven to be faster, easier, low cost, and gave result as well as the reference method published by the United States Pharmacopoiea (USP). A first-derivative UVDS and peak to baseline technique at wavelength of 312 nm was used. The content of reserpine in tablets was found to be 0.2260 ±0.0033 mg by UVDS and 0.2301 ±0.0051 mg by the USP methods. Statistical test between UVDS and USP methods showed no significant difference, both for F-test and t-test at 95 % confidence level. Evaluation of analytical performance included some parameters, such as accuracy based on recovery that was 99.18 - 101.13 %. Precision showed as relative standard deviation (RSD) was 1.91 %, linear correlation was 0.9998 in the range of 10 - 50 µg/mL. Limit of detection and limit of quantitation was 0.8868 µg/mL and 2.6874 µg/mL, respectively. 79 23rd-25th June 2010 3rd ICYC 2010 Universiti Sains Malaysia ANA-P8 PREPARATION OF METHACRYLATE-ESTER-BASED ULTRA LOW FLOW RESISTANCE MONOLITHIC CO...
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