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Unformatted text preview: s of solid sulfonic acids have been created in recent years, there have been only a few reports about their applications as catalyst in chemical transformations. Furthermore, to the best of our knowledge there is no report on the use of these materials as nanocatalysts in the synthesis of substituted imidazoles under solvent -free conditions. We have developed a simple and highly efficient practical method for the one -pot synthesis of the substituted imidazoles using the MCM -41-SO3H under solvent-free conditions. The yields of products are very good to excellent and the use of toxic solvents is avoided. Simple work -up and a high degree of MCM-41-SO3H reusability are interesting points of the developed procedure. And we expect to find more applications for this catalytic system in organic synthesis. Scheme 1
N NH4OAc + A rC H O + (PhNH2) MCM-41-SO3H, Neat 100°C, 15-35 min N R Ar O O + 207 23rd-25th June 2010 3rd ICYC 2010 Universiti Sains Malaysia ORG-P19 ANTI-INFLAMMATORY AND ANTI-MICROBIAL CONSEQUENCE OF DILLENIA INDICA LINN FRUIT
1 M Asheka, MMI Talukder, JMA Hannan and SAM Khairul Bashar
1 1 2 2 1, 2 Maple Leaf International School, Dhanmondi, Dhaka, Bangladesh Department of Pharmacy, North South University, Dhaka, Bangladesh E-mail: [email protected] Dillenia indica Linn, Common names: Elephant-apple, Bangla: Chalta, Syn. P. lanigerum; Family Dilleniaceae) is a more or less deciduous tree growing up to 10 meters or more in height, with a few wide-spreading branches. The fruit, which is made of ripened carpels and enclosed by greatly enlarged and thickened imbricating sepals, is large, somewhat rounded or broadly ovoid, 12.5 to 15 centimeters in diameter, yellowish green, hard and tough. It is very watery, 86.4 % being water, with 10 % of insoluble matter, and very little that is nutritious. The calyces of the fresh ripe fruit have the following composition: Moisture 86.40 %, alcoholic extract 3.00 %, water extract 0.37 %, and insolubles 10.23 %. The fruit is slightly laxative, but...
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This note was uploaded on 02/17/2011 for the course CHEMISTRY 101 taught by Professor Csr during the Spring '11 term at University of Louisville.
- Spring '11