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Unformatted text preview: olume ratio 44:54:2 . Five concentrations of extractive solutions were prepared; consist of 0 ppm, 10 ppm, 50 ppm, 100 ppm and 1000 ppm. The rubber woods (Hevea brasiliensis) blocks were then treated with the extractive solution and exposed to the white rot fungi for 12 weeks. Data of the percentage of rubber wood weight loss after 12 weeks exposure to the fungi were analyzed using two way ANOVA. The result showed that the use of different solvent did not have significant effect on the percentage of rubber wood weight loss ( P>0.05). However, the use of different extractive concentration gave significant effect ( P<0.05) in which rubber woods treated with 1000 ppm extractive solution showed the lowest percentage weight loss compared to 0, 10, 50, and 100 ppm. The result also showed that the percentage weight loss of the rubber wood blocks treated with balau wood extract were not depend on the solvent and the extractive concentration used. This study indicate that balau wood extract were effective in inhibit the growth of white rot fungi. 209 23rd-25th June 2010 3rd ICYC 2010 Universiti Sains Malaysia ORG-P23 A FACILE, RAPID SYNTHESIS OF NOVEL HIGHLY FUNCTIONALIZED BENZIMIDAZOLE DERIVATIVES UNDER MICROWAVE IRRADIATIONS
1 Natarajan Arumugam, Shafida Abd Hamid, Hasnah Osman and *Aisyah Saad Abdul Rahim
1 2 3 1, 2 School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800 Pulau Pinang, Malaysia Kulliyyah of Science, International Islamic University Malaysia (IIUM), Jalan Istana, Bandar Indera Mahkota, 25200 Kuantan, Pahang, Malaysia 3 School of Chemical Sciences, Universiti Sains Malaysia, 11800 Pulau Pinang, Malaysia E-mail: [email protected] Benzimidazole nucleus is the key building block for a variety of compounds that play crucial roles in the function of a number of biologically important molecules. In particular, benzimidazole derivatives act as potential anticancer agents. In view of their importance in the field of drug discovery, a series of novel highly functionalized benzimidazole derivatives have been accomplished in four steps by the reaction of ethyl amino butylbenzoate, which was derived from 4 -fluro 3-nitro benzoic acid with various subsituted sodium bisulfite adduct of benzaldehyde under microwave irradiations in good yield. The structure of these compounds was elucidated by IR, NMR and X-ray crystallographic studies. ORG-P24 SYNTHESIS AND CHARACTERIZATION OF ISOFLAVONE DERIVATIVES Tze-N...
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This note was uploaded on 02/17/2011 for the course CHEMISTRY 101 taught by Professor Csr during the Spring '11 term at University of Louisville.
- Spring '11