This preview shows page 1. Sign up to view the full content.
Unformatted text preview: H2 C=O acid sites OH isopulegol H2 OH E/Z-citral (±)-citronellal menthol In another cascade reaction, the hydrogenation of 4-tert-butylphenol and p-cresol to the corresponding alkylcyclohexanol was investigated.
OH 2H2 Rh R R = tert-butyl or methyl R enol
ads OH O iPrOH Zr R ketone OH + OH R cis-alcohol R trans-alcohol The talk will discuss the investigation into suitable catalytic systems for the formation of the desired products with good yields. 48 3rd ICYC 2010 Universiti Sains Malaysia KN-09 23rd-25th June 2010 NITROALKANES AS STARTING CARBANIONS IN THE MICHAEL REACTION R Ballini, S Gabrielli and A Palmieri School of Science and Technology, Chemistry Division, Via S. Agostino 1, Camerino 62032, Italy E-mail: email@example.com Conjugate addition of carbon nucleophiles to electron -poor alkenes is of paramount importance among the large body of synthetic processes. Nitroalkanes are a valuable source of stabilized carbanions since the high electron-withdrawing power of the nitro group provides an outstanding enhancement of the hydrogen acidity at the α-position (cf. pKa MeNO2 = 10). Nitronate anions 2 that can be generated from nitroalkanes 1 using a wide range of bases act as carbon nucleophiles with common Michael acceptors 3, leading to carbon-carbon bond (Figure 1). These reactions constitute the key starting steps for a variety of synthetic process for the preparation of a huge series of fine chemicals (Figure 2). The main results will be reported.
NO2 NO2 EWG R R1 O2N EWG base
R R1 R 3 2
R1 1 Fig. 1
Furans 4 Lactones Spiroketals NO2 Pyrroles
R R1 +
EWG Cyclopentenes F i g. 2 Benzenes 49 23rd-25th June 2010 3rd ICYC 2010 Universiti Sains Malaysia KN-10 HOLLOW FIBRE-LIQUID PHASE MICROEXTRACTION: GREEN SAMPLE PREPARATION STRATEGY FOR THE ANALYTICAL DETERMINATION OF SELECTED ANALYTES Bahruddin Saad School of Chemical Sciences, Universiti Sains Malaysia, 11800 Pulau Pinang, Malaysia E-mail: firstname.lastname@example.org The hollow fibre-liquid phase microextraction (LPME), introduced by Pedersen -Bjergaard and Rasmussen of the University of Oslo in 1999, has received much attention lately. In this technique, the extracting solvent is trapped inside the pores of a porous polypropylene hollow fiber (typical properties: porosity, 70 %; pore size, 0.2 μm; wall thickness, 200...
View Full Document
This note was uploaded on 02/17/2011 for the course CHEMISTRY 101 taught by Professor Csr during the Spring '11 term at University of Louisville.
- Spring '11