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Unformatted text preview: sized from the reactions of different metallated agents such as acetoxy Co(II), Ni(II), and Cu(II) derivatives of m -phenylene diamine, benzoic acid, p-amino benzoic acid, anthranilic acid, m-aminophenol also, acetoxy Hg(II) derivatives of phenol and toluene. All the new compounds were detected and found to have antimicrobial activities. The 1 structures were confirmed by elemental analyses, IR, UV/Vis, H-NMR and mass spectra.
O O S O O HO O H CH3 OH O O OH Co S O + OH CH3 O Co O H3C O HO OH O HO CH3 O OH O HO CH3 O ORG-O4 PROLINE-BASED CHIRAL IONIC LIQUIDS AS AN EFFECTIVE ORGANOCATALYSTS FOR ASYMMETRIC MICHAEL REACTIONS
1 Emmy M. Omar, Allan D. Headley and Mohd Basyaruddin Abdul Rahman 2 1 1 Department of Chemistry, Faculty of Science, Universiti Pu tra Malaysia, 43400 UPM Serdang, Selangor, Malaysia 2 Department of Chemistry, Texas A&M University -Commerce, Commerce, TX 75429-3011, USA E-mail: [email protected] Ionic liquid pyrrolidine-based organocatalyst has been developed to be a very effective catalyst for the asymmetric Michael addition reactions involving the addition of aldehydes to nitroolefins. This shown to be efficient as organocatalyst due to it high enantio- and diastereoselectivities obtained. Compared to the addition reaction involving ketones to nitroolefines using the same catalyst, enantioselectivities were slightly lower and could have been due to the lack of bulkiness of the aldehydes to assist in selectivity toward enantiomeric excess (ee). Ionic liquid proline -based sulfonamide organocatalyst has been developed for the asymmetric Michael addition reactions of various aldehydes to nitrostyrenes. Without any additive, the reaction was found to be very effective in giving excellent yields (up to 90 %), shorten time constraint (3 - 5 hours), and high diastereoselectivities (syn/anti ratio up to 95:5). This chiral ionic liquid catalyst has a special ability in the outcome of the asymmetric organocatalyst. 186 3rd ICYC 2010 Universiti Sains Malaysia ORG-O5 23rd...
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This note was uploaded on 02/17/2011 for the course CHEMISTRY 101 taught by Professor Csr during the Spring '11 term at University of Louisville.
- Spring '11