Acetic acid the reaction mixture was irradiated

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Unformatted text preview: mical Science, Faculty of Science, Universiti Tunku Abdul Rahman, Jalan Universiti Bandar Barat, 31900 Kampar, Perak, Malaysia 2 Department of Science, Faculty of Engineering and Science, Universiti Tunku Abdul Rahman, Jln Genting Klang, Setapak, 53300 Kuala Lumpur, Malaysia 3 Liquid Crystal Research Laboratory, School of Chemical Sciences, Universiti Sains Malaysia, 11800 Pulau Pinang, Malaysia Email: [email protected] A new homologous series of liquid crystals containing benzoxazole core with even number of carbons (n) at terminal ester chain have been successfully synthesized and isolated. The structure of the title 1 13 compound was postulated using FT-IR, H NMR, C NMR and electron-ionization mass spectroscopic techniques. The phase transition temperatures and associated enthalpy changes were determined using differential scanning calorimetry. The textures of mesophases were observed under optical polarizing microscope attached with a Linkam hotstage. All the compounds are enantiotropic liquid crystals exhibiting smectic A phase. Cl N N O C Cl-n-BZX n = 12, 14, 16, 18 O O Cn-1H2n-1 1 198 3rd ICYC 2010 Universiti Sains Malaysia ORG-P4 23rd-25th June 2010 SHORT AND EFFICIENT SYNTHESIS OF GONIOTHALAMIN FROM (3,4-DIHYDRO-2H-PYRAN-2-YL)METHANOL Mazlin Mohideen, Nik-Salmah Nik-Salleh, Suraya Zulkepli, Mohd Zulkefeli Mat Jusoh, Jean-Frédéric Faizal Weber and A. F. M. Motiur Rahman iKUS, Faculty of Pharmacy, University Technology MARA (UiTM), Shah Alam, Selangor 40450, Malaysia. E-mail: [email protected] Synthesis of Goniothalamin (3 steps) and its derivatives has been synthesized deriv ed from commercially available (3,4-dihydro-2H-pyran-2-yl)methanol. The method is novel, simple and convenient as well as proceeds in good overall yields (37 %). The corresponding aldehyde of (3,4 -dihydro-2H-pyran-2yl)methanol is unstable. Therefore, the reaction mixture was subjected to proton NMR spectroscopy to confirm the presence that aldehyde and reacted for the next step without further puri...
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This note was uploaded on 02/17/2011 for the course CHEMISTRY 101 taught by Professor Csr during the Spring '11 term at University of Louisville.

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