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Unformatted text preview: soff PETRONAS Research Sdn Bhd, Research & Technology Division, PETRONAS Lot 3288 & 3289, Off Jalan Ayer Itam, Kawasan Institusi Bangi, 43000, Kajang, Selangor, Malaysia E-mail: firstname.lastname@example.org Impact of biodiesel fatty acid methyl ester (FAME) on lubricant has been investigated using laboratory bench tests. Different levels and types of biodiesel FAMEs based on rapeseed (RME), soybean (SME) and palm (PME) have been employed in this study. The lubricant performance areas under study are oxidation stability, corrosion and deposit. Laboratory bench tests such as High Temperature Corrosion Bench Test (HTCBT), Pressure Differential Scanning Calorimeter (PDSC) and Thermo oxidation Engine Oil Simulation Test (TEOST) will be deployed to assess the lubricant performance with the presence of the biodiesel FAMEs. The effect of chemical composition of biodiesel FAMEs to lubricant performance will be discussed in details. IND-O2 NEWLY SYNTHESIZED PALM OIL ESTERS FOR TRANSDERMAL DELIVERY OF KETOPROFEN M.H.F. Sakeena, Elrashid S.M., Munavvar A.S. and Azmin M.N. School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800 Pulau Pinang, Malaysia E-mail: email@example.com The aim of this study is to investigate the in vitro permeation of ketoprofen from the formulated nano emulsions through excised rat skin and the efficacy of nano -emulsions formulated as anti-inflammatory products. Palm Oil Esters (POEs) newly introduced oil by Universiti P utra Malaysia researchers was chosen for use as the oil phase of the nano-emulsion this study, as it was reported to be a good vehicle for pharmaceutical use. Permeation of ketoprofen nanoemulsion by in vitro through hairless rat skin was evaluated in Frantz diffusion cells and compared with marketed product Fastum gel®. Effects of limonene added to the nano-emulsion formulations at the level of 1 %, 2 %, and 3 % on skin permeation of ketoprofen through the skin also evaluated. The selected optimized formul ation was further studied for anti-inflammatory effe...
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- Spring '11