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Unformatted text preview: hich is a distinctive feature of MCM -41. The BET 2 -1 specific surface area of RHA-MCM-41 was found to be 1165 m g . It had a narrow pore diameter, centered on 2.7 nm in agreement with the TEM results. The EDX analysis showed ruthenium was incorporated in the silica matrix and it was confirmed by the mapping image showing a homogeneous distribution of the metal. MAT-P7 INVESTIGATION OF THE STABILITY PARAMETERS OF NLC PREPARED WITH HOT HOMOGENIZATION PROCESS BY USING TAGUCHI’S METHOD
1 Pao-Chi Chen, H. C. Chen, J. Pang, P. K. Xu, M. C. Jian and W. R. Liao 1 3 2 2 2 2 Graduate School of Engineering, Lunghwa University of Science and Technology Department of Chemical and Materials Engineering, Lunghwa University of Science and Technology 3 Taiwan AC Scientific Inc. 300, Wan-Shou Rd., Sec. 1, Kueishan, Taoyuang, Taiwan E-mail: email@example.com 1 The present study focuses on the preparation, by hot homogenization process, and physical characterization of NLC (nanostructured lipid carriers) aqueous dispersions concerning their particle size, zeta potential and rheological properties for different operating conditions, i.e., pre -emulsion time, pressure, cycle time, and storing temperature. The formula was given from preliminary study containing black currant oil, canauba wax, decyl glucoside and pentylene glycol. In here, we explore the effect of process parameters on the properties of NLC and use Taguchi’s method to find the optimum conditions preparing NCL with the aid of S/N ratio for a given formula. The stability te sts were carried out from 1 to 90 days. The results showed that the significant sequence influencing the particle size is C(cycle ti me) >B(pressure) >A(pre-emulsion time), while the significant sequence influencing the zeta -potential is A >C >B. Evidences showed that all zeta-potential measurements obtained in this study were higher than 30 mV, indicating that the stability of NLC prepared in here comes through the tests. From viscoelastic dynamic analysis, G’ is always higher th...
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This note was uploaded on 02/17/2011 for the course CHEMISTRY 101 taught by Professor Csr during the Spring '11 term at University of Louisville.
- Spring '11