Unformatted text preview: s. Anti -tuberculosis activity can be estimated with in vitro anti-tuberculosis test against mycobacterium tuberculosis. Anticancer potency of the plant extract can be estimated with toxicity test against Artemia salina. Lichens, unique plant that is a combination of alga and fungus, constitute important sources for prospecting new bioactive molecules. Group of compound in lichen body can be estimated with sp ecific color test for lichen. In some place, like China and India lichen used intensively as traditional medicine. Many variety of lichen growth in Indonesia and south East Asia region, but until now, haven’t used intensively as medicine. Lichen Parmotrema tinctorum. is common in south east Asia region. In this paper we present the recent result of our group focus to obtain new active compound from P. tinctorum. In this part, we will report about the result of compound group screening test, dichloromethan e extract bioactivity test as anti tuberculosis against Mycobacterium tuberculosis H37RV and toxicity against Artemia salina, and some compound has been isolated from dichloromethane extract. Result of specific color test showed that pulvinic acid derivative and phenolic group maybe present in hexane and dichloromethane extract, but dichloromethane extract has higher compound concentration than hexane extract. Ethyl acetic and acetone extract have phenolic groups, pulvinic acid derivative, depside and xant hone with two free hydroxyl groups at meta position. The result of bioactivity test of dichloromethane extract showed that, dichloromethane extract has toxic to Artemia salina, but dichloromethane extract has not antituberculosis potency. Three depside has been isolated. NAT-O8 CHEMICAL CONSTITUENTS FROM THE RHIZOMES OF HOMALOMENA SAGITTIFOLIA
1 Abdul Hamid, *K.C. Wong and S. Baharuddin 1, 2 1 2 School of Chemical Sciences, Universiti Sains Malaysia, 11800 Pulau Pinang, Malaysia School of Biological Sciences, Universiti Sains Malaysia, 11800 Pulau Pinang, Malaysia E-mail: [email protected] Homalomena sagittifolia Jungh belongs to aracae family. It is an aromatic herb commonly known as kemoyang in Malaysia. It is a sm...
View Full Document
This note was uploaded on 02/17/2011 for the course CHEMISTRY 101 taught by Professor Csr during the Spring '11 term at University of Louisville.
- Spring '11