This preview shows page 1. Sign up to view the full content.
Unformatted text preview: the further fractionation steps. The hexane: ethyl acetate 95: 5 fraction of the extract showed the highest neuroprotective activity. Further purification and structural elucidation of compounds were performed on this fraction. Extensive chromatographic analysis have resulted in the isolation of nine prenylated coumarins (which includes compounds 5,7-dihydroxy-8-(2-methylbutanoyl)-6-[(E)-3,7-dimethylocta-2,6dienyl]-4-phenyl-2H-chromen-2-one 1 and 5,7-dihydroxy-8-(3-methylbutanoyl)-6-[(E)-3,7-dimethylocta2,6-dienyl]-4-phenyl-2H-chromen-2-one 2) which shall be discussed briefly in this presentation. OH OH HO O O O HO O O O 1 2 184 3rd ICYC 2010 Universiti Sains Malaysia 23rd-25th June 2010 ORAL PRESENTATION (ORGANIC)
ORG-O1 IMPROVED LOW TEMPERATURE PROPERTIES OF 2 -ALKYL 9-HYDROXY-10-ACYLOXYSTEARATE DERIVATIVES Jumat Salimon and Nadia Salih School of Chemical Sciences & Food Technology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, Malaysia E-mail: [email protected] Low-temperature properties need improvement before biolubricant oils can receive wider recognition as biodegradable of base oil. In the present work in order to produce oleic acid based biolubricants with good flash and low pour points, epoxidized oleic acid (EOA) was chemically modified. Epoxidized oleic acid was reacted with various fatty acids in the presence of p-toluenesulfonic acid (PTSA) as a catalyst to give a ring-opened intermediate product. Different alcohols were used to esterify the carboxylic acid groups in the ring-opened products. Some physical properties of each synthesized compound were determined through its pour point, viscosity and flash point values. Furthermore, the chemical structure 1 13 for the synthesized compounds were determined through their FTIR, H-NMR and C-NMR spectra. ORG-O2 DESIGN, SYNTHESIS AND EVALUATION OF NOVEL CONDENSED QUINOLINES AS ANTIMICROBIAL AGENTS G. K. Nagaraja and Reshma Kayarmar Post-Graduate Department of Studies and Research in Chemistry, Mangalore University , Mangalagangothri, Mangalore- 574 19...
View Full Document
This note was uploaded on 02/17/2011 for the course CHEMISTRY 101 taught by Professor Csr during the Spring '11 term at University of Louisville.
- Spring '11