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Unformatted text preview: is apt. to induce diarrhea, if too freely indulged in. The juice of the fruit, mixed with sugar and water, is used as a cooling beverage in fevers and as a cough mixture, a cooling beverage as also for toning up the nervous system. In the present investigations, the ethanolic extract of Dillenia indica Linn. fruit extracts were subjected to screening for the toxicity in albino rat s and mice. The study with ethanolic extract showed significant results. Extracts demonstrated weak antimicrobial activity against a wide range of Gram -positive and Gram-negative bacteria and fungi. We have carried out pharmacological study by Plethysmo Meter (Anti-inflammatory Tester), Rat Metabolic Case, Hot and Cold Plate respectively. Preliminary phytochemical tests, TLC has also been carrying out. ORG-P20 SYNTHESIS OF STYRYLLACTONE DERIVATIVES Suraya Zulkepli, Mazlin Mohideen, Nik-Salmah Nik-Salleh, Mohd Zulkefeli Mat Jusoh, Jean-Frédéric Faizal Weber and *A. F. M. Motiur Rahman iKUS, Faculty of Pharmacy, Universiti Teknologi MARA (UiTM), 42300 Puncak Alam, Selangor, Malaysia E-mail: email@example.com A series of arene phosphonium halides has been synthesized and tested their ability to undergo Wittig coupling reactions in presence of sodium hydride (NaH). A couple of five - and six- membered aldehyde were synthesized and used them for the next step without further purification, most of the aldehydes were not stable, therefore, we have confirmed the presence of aldehyde by proton nuclear magnetic 1 resonance ( H NMR) spectroscopy and reacted with the above mentioned Wittig reagents. Various five and six-membered styryllactone derivatives were synthesized successfully using a new method starting from aldehyde and Wittig reagents. A corresponding series of E/Z styryllactone isomers were obtained in good yields.
PPh3Br O O n = 1,2 R O O R O n = 1,2 208 3rd ICYC 2010 Universiti Sains Malaysia ORG-P21 23rd-25th June 2010 SYNTHESIS, CHARACTERIZATION AND LIQUID CRYSTALLINE PROPERTIES OF 5-(ALKOXY)-2-((4 (PHENY...
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