Tapisoides species which are goniothalamin and

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Unformatted text preview: k, Boey Peng Lim and Dafaalla M.H. Ali 1 2 2 School of Chemical Sciences, Universiti Sains Malaysia, 11800 Pulau Pinang, Malaysia Department of Chemistry, College of Science, Sudan University of Science and Technology, P. O. Box 407 Khartoum, Sudan E-mail: chiangpn85@yahoo.com 1 Hibiscus rosa-sinensis Linn, from the family of Malvaceae, best known as ‘Bunga Raya’ in Malaysia, had been used as a traditional medicinal plant in Southeast Asia, China and India for a very long time. Various parts of the plant are proven to have medicinal effects such as in cough treatment, bronchial catarrh, diarrhea and also in fertility control. Many research works done on the leaves and flowers of Hibiscus rosa-sinensis Linn. reported that the plant exhibits hair growth promoting properties, in vitro and in vivo. In order to rationalize its use as a hair growth stimulator, the dried leaves of Hibiscus rosasinensis Linn. was extracted with petroleum ether, ethyl acetate and methanol to obtain crude extracts of different solvents. The crude extracts were fractionated using silica gel column chromatography and analyzed by FT-IR, NMR and GC. 183 23rd-25th June 2010 3rd ICYC 2010 Universiti Sains Malaysia NAT-P25 BIOASSAY-GUIDED ISOLATION OF NEUROPROTECTIVE AGENTS FROM MESUA ELEGANS 1 Chan Gomathi, Daniel Wong Zin Hua, Habsah Abdul Kadir and Khalijah Awang 2 2 1 2 Department of Chemistry, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia Department of Biochemistry, Institute of Biological Science, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia E-mail: changomathi@um.edu.my 1 A study of the bark from Mesua elegans (King) Kosterm was performed. The hexane extract showed potent neuroprotective activity. Thus, the active extract was subjected to chromatographic analysis to purify and detect the possible active components. The TLC of the active hexane extract showed merely 1 one spot at several different solvent systems. However the H NMR analysis of the crude suggested that more than one compound may be present. The hexane extract had been carried forward for...
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This note was uploaded on 02/17/2011 for the course CHEMISTRY 101 taught by Professor Csr during the Spring '11 term at University of Louisville.

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