Lecture_3 _Mitosis_&_Meiosis_2011

Lecture_3 _Mitosis_&_Meiosis_2011 - Mitosis Meiosis...

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Mitosis & Meiosis Jan 14 th 2011
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Review DNA is the genetic material DNA is a double-stranded helix DNA has 5’ and 3’ ends ( polarity ) DNA replicates semi- conservatively DNA Polymerase catalyzes DNA synthesis Telomeres cap the end of
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Packaging DNA Human genome: ~ 3 billion nucleotides long, ~ 1m Nucleosome: 8 Histones form protein core, DNA wraps around 2x
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Packaging DNA
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Chromosomes PROKARYOTES typically have a single chromosome without a nucleus – do not undergo sexual cell divisions EUKARYOTES typically have a set of chromosomes from their mother and a set from their father Different versions of the same gene on each set of chromosomes are called ALLELES
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Alleles
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Chromosome Components
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Chromosomes Can Be Seen
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Cell Division When Cells divide they face two problems
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Cell Division When Cells divide they face two problems They have to REPLICATE their genetic material
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Cell Division When Cells divide they face two problems They have to REPLICATE their genetic material They have to SORT that material evenly into daughter cells
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Two major phases Interphase: Cell growth (G1, G2) Chromosomes duplicate (S) Mitotic: Cell division (M) The Cell Cycle
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