Lecture_7_Allelism_2011

Lecture_7_Allelism_2011 - Allelism Jan 26th, 2011...

Info iconThis preview shows pages 1–10. Sign up to view the full content.

View Full Document Right Arrow Icon
Allelism Jan 26 th , 2011
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Announcements 1 st homework due Friday (by 4 pm) in your TA’s mailbox (located in Coker hallway) Answer sheet will be available online Friday evening 2 nd homework will be posted Friday (by 5 pm) First midterm Friday Feb 4 th
Background image of page 2
Review SEX DETERMINATION can be controlled by a variety of systems (XX-XO; XX-XY; ZZ-ZW etc.) SEX-LINKED genes are inherited in novel patterns Chromosomal sex determination systems often require DOSAGE COMPENSATION systems. X-INACTIVATION is used as a dosage compensation system in humans
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Review
Background image of page 4
Dosage Compensation X chromosome carries lots of genes Dosage imbalance can be detrimental Flies double male X gene activity Worms halve female X gene activity
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
X inactivation Dermal dysplasia Reduced sweat gland maternal chromosome paternal chromosome embryo Not always random – marsupials only inactivate the paternal X Calico Only female cats
Background image of page 6
XIST encodes a large RNA . XIST RNA coats the X chromosome with the active XIST gene XIST RNA inactivates the genes on that chromosome. XIST RNA does not travel to the other X chromosome. X inactivation by XIST
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Allelism Complete Dominance Incomplete Dominance Codominance Recessive Lethal Alleles
Background image of page 8
Complete Dominance •F 1 shows dominant phenotype •Both phenotypes segregate in F 2
Background image of page 9

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 10
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 02/17/2011 for the course BIOL 202 taught by Professor Kieber-hogan during the Spring '08 term at UNC.

Page1 / 28

Lecture_7_Allelism_2011 - Allelism Jan 26th, 2011...

This preview shows document pages 1 - 10. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online