Lecture_8_Complementation_2011

Lecture_8_Complementation_2011 - Complementation Jan 28th,...

Info iconThis preview shows pages 1–6. Sign up to view the full content.

View Full Document Right Arrow Icon
Complementation Jan 28 th , 2011
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Announcements 1 st homework due today, Friday (by 4 pm). 2 nd homework posted today. First midterm Feb 4 th – covers through today, Jan 31 st , Lecture 9.
Background image of page 2
Review Alleles can be fully dominant, INCOMPLETELY DOMINANT, or CODOMINANT to one another. A single genotype can result in several phenotypes; this is called PLEIOTROPY . Different pleiotropic phenotypes from the same gene can have different DOMINANCE relationships Some alleles are RECESSIVE LETHAL . The CHI SQUARE test can be used to determine if two data sets are statistically different.
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Interaction of Genes, Proteins in Common Pathways Archibald Garrod, 1902-1908 Examined recessive mutations causing metabolic defects Alkaptonuria (black urine disease) (AKU) Proposed the mutation prevented the converion of Homog Acid to maleylacetoacetic acid.
Background image of page 4
Heralded the science of Molecular Biology 1940s – work with the haploid organism: Neurospora crassa 1)Irradiated N. crassa (mutagen) 1)Found auxotrophic mutant (grows on complete media or minimal media supplemented with a specific nutrient). Auxotrophic : the ability to synthesis a compound is compromised and therefore the nutrient must be supplied exogenously. 3) Determine that each mutant arises from single gene
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 6
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 02/17/2011 for the course BIOL 202 taught by Professor Kieber-hogan during the Spring '08 term at UNC.

Page1 / 23

Lecture_8_Complementation_2011 - Complementation Jan 28th,...

This preview shows document pages 1 - 6. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online