Lecture_9_Prokaryotic_Genetics_2011

Lecture_9_Prokaryotic_Genetics_2011 - Prokaryotic Genetics...

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Unformatted text preview: Prokaryotic Genetics Jan 31 st , 2011 Helicobacter pylori, a prokaryote and the dominant cause of eptic ulcer disease, shown adhering to a eukaryotic gastric c Announcements • First midterm Friday Feb 4 – covers through Jan 31 st – Bring a writing utensil – non-erasable pen – Bring a SIMPLE calculator – DO NOT bring a cell phone or PDA Review • You can determine if two mutations are in the same gene by performing a COMPLEMENTATION TEST . • Mutations in DIFFERENT genes COMPLEMENT one another. • Mutations in the SAME gene do NOT complement ( NONCOMPLEMENT ) one another. • Complementation test only work with RECESSIVE alleles. • There are exceptions to the complementation test such as NONALLELIC NONCOMPLEMENTATION and INTRAGENIC E. Coli is a Model Prokaryote • No nucleus • Lives in your gut • 4000 genes • Circular genome • 4.6 million base pairs • Haploid • Divides mitotically Bacteria use novel mechanisms to exchange genetic information. Bacterial Sex Genetic Transfer in Bacteria Conjugation (by mating) Transformation (by scavenging) Transduction (by infection) njugation - Lederburg and Tatu...
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Lecture_9_Prokaryotic_Genetics_2011 - Prokaryotic Genetics...

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