exam 3 Fall 2007

exam 3 Fall 2007 - BBMB 404DL Fall 2007 Exam 3 1. Which of...

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BBMB 404DL – Fall 2007 Exam 3 1. Which of the following is NOT involved in the specificity of signal transduction? a) structure of receptor molecules b) location of receptor molecules c) structure of signal molecules d) interactions between receptor and signal molecules e) transmembrane transport of signal molecules by receptor molecules 2. Which receptors share a common cross-phophorylation signaling mechanism? a) adrenaline and insulin receptors b) adrenaline and EGF receptors c) insulin and EGF receptors 3. Which of the following is NOT a step at which amplification occurs in signalling? a) GTP exchange (e.g. by GPCR/serpentine receptors) b) activation of effectors by G proteins c) phosphorylation of effectors by protein kinases d) release of Ca 2+ by IP 3 receptor e) production of cAMP by adenylate cyclase 4. What best describes why GTP is considered a 'clock or timer' for G-proteins? a) it diffuses away after a specific time interval b) it is regulated by energy c) it is hydrolyzed to GDP and P i d) none of the above 5. Modular signaling domains, such as the phosphotyrosine binding SH2 domain, can operate in many different pathways. This is best described as a function of: a) cross-talk between pathways b) the convergence of multiple signaling pathways on a common response c) the different specificities of related modular domains d) the inherent tendency to exhibit a uniform response (i.e. homeostasis) 6. Phospholipase C ß cleaves phosphatidylinositol-4,5-bisphosphate to generate diacylglycerol and inositol-1,4,5-trisphosphate second messengers that: a) act completely independently b) have opposing effects c) act synergistically to amplify a response d) are both membrane bound 7. Which of the following molecules carries the most energy? A a) b) c) ATP d) O O O H HO CH 2 OH OH H OH OH H H H CH 2 OPO 3 2- OH H OPO 3 2- O
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8. What is the most common ‘handle’ for carriers in central/intermediary metabolism?
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This note was uploaded on 02/17/2011 for the course BBMB 404 taught by Professor Staff during the Spring '08 term at Iowa State.

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exam 3 Fall 2007 - BBMB 404DL Fall 2007 Exam 3 1. Which of...

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