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biochem - H OMEWORK 4 1 SHAN T H I N I ARU M UGA M H...

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HOMEWORK 4 SHANTHINI ARUMUGAM 2 I. Compound: 2-Aminoimidazoles A. other names of compound and (where you got the structure): 2-aminoimidazole or triazole ( Chemical book) B. Formula: C3H5N3 C. Structural formula: see figure D. Primary use: pharmaceutical intermediates II. Article Reference: A. Title: "Synergistic Effects between Conventional Antibiotics and 2-Aminoimidazole- Derived Antibiofilm Agents" B. Author: Christian Melander, Steven A. Rogers, Robert W. Huigens III and John Cavanagh, NC State University C. Journal: Online in March 8 editions of Antimicrobial Agents and Chemotherapy D. Synopsis: Researchers writing in Antimicrobial Agents and Chemotherapy have found a chemical compound that, when used in conjunction with usual antibiotics , is effective in destroying biofilms produced by antibiotic-resistant strains of bacteria such as the Staphylococcus strain MRSA and Acinetobacter. The effective in breaking up the biofilms created by certain bacterial strains by combining a
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