1Gastrointestinal Pathophysiology Exam 2006 Tufts University School of Medicine Instructions: please select the one BEST answer. 1.Three days into the hospitalization for an acute illness a CT scan is performed on a 32 year old woman. She initially presented to the emergency room with severe periumbilical pain, nausea, and vomiting. She denied any alcohol use and was on no medications. She had previously been feeling well. She was treated with intravenous fluids and kept nothing by mouth. An initial ultrasound exam of the abdomen revealed gallstones within the gallbladder and a mildly dilated common bile duct. Because her symptoms persisted and she developed a fever the CT scan was obtained. Which of following statements best describes the pathophysiology of this condition? A.Obstruction of the cystic duct due to gallstones B.Activation of pancreatic enzymes within the pancreas C.Obstruction of the pancreatic duct due to proteinaceous plugs D.Reduction in pancreatic enzyme synthesis and secretion E.Reduction in stimulation of intracellular calcium signaling pathways 2.A 52 year old man has had heartburn for over 20 years. He reports no dysphagia or odynophagia. An upper endoscopy shows no significant hiatal hernia. Which of the following esophageal motility test findings would you most likely expect to see in this patient?
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