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Chapter 30.pe - Chapter30 AdrenergicAgents &Wilkins...

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Copyright  ©  2008 Lippincott Williams & Wilkins. Chapter 30 Adrenergic Agents
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Copyright  ©  2008 Lippincott Williams & Wilkins. Adrenergic Agonists Definition Called sympathomimetic drugs because they mimic the  effects of the sympathetic nervous system (SNS) Therapeutic and adverse effects  Related to their stimulation of adrenergic receptor sites Indications  Vary from ophthalmic preparations for dilating pupils to  systemic preparations for shock
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Copyright  ©  2008 Lippincott Williams & Wilkins. Physiologic Responses of  Adrenergic Agonists
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Copyright  ©  2008 Lippincott Williams & Wilkins. Alpha- and Beta-Adrenergic Agonists and Their  Indications Epinephrine ( Adrenalin, SusPhrine ): treats shock, glaucoma;  prolongs effects of regional anesthetic Norepinephrine ( Levophed ): treats shock or is used during cardiac  arrest to stimulate sympathetic activity Dopamine ( Intropin ): treats shock  Dobutamine ( Dobutrex ): treats congestive heart failure Ephedrine ( Pretz-D ): treats seasonal rhinitis, hypotensive episodes Metaraminol ( Aramine ): synthetic agent similar to norepinephrine;  treats shock or induces sympathetic activity during cardiac arrest
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Copyright  ©  2008 Lippincott Williams & Wilkins. Alpha- and Beta-Adrenergic Agonists Actions The effects of the drug are mediated by the  adrenergic receptors in target organs; heart rate  increases, bronchi dilate, vasoconstriction occurs,  intraocular pressure decreases, and glycogenolysis  occurs throughout the body Indications Treatment of hypotensive shock, bronchospasm, and  some types of asthma
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