Chapter 41.pe - Chapter41 ReproductiveSystem &Wilkins...

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Copyright  ©  2008 Lippincott Williams & Wilkins. Chapter 41 Drugs Affecting the Male  Reproductive System
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Copyright  ©  2008 Lippincott Williams & Wilkins. Drugs Used to Affect the  Male Reproductive System Male steroid hormones or androgens Act like testosterone Develop male sexual characteristics  Male sex hormone or anabolic steroids Synthetic testosterone preparations have more  anabolic effects than androgenic effects  Tissue building Drugs to improve penile dysfunction
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Copyright  ©  2008 Lippincott Williams & Wilkins. Sites of Action of Drugs Affecting the  Male Reproductive System 
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Copyright  ©  2008 Lippincott Williams & Wilkins. Signs and Symptoms of Adverse Effects of  Androgens/Anabolic Steroids Swelling in fingers or legs Continual erection Uncontrollable sex drive Yellowing skin Fever, chills, and rash Chest pain and difficulty breathing Hoarseness Loss of hair or growth of facial hair in women
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Copyright  ©  2008 Lippincott Williams & Wilkins. Androgens and Their Indications Testosterone ( Duratest, Testoderm,  others)  Hypogonadism; breast cancer Danazol ( Danocrine ) Blocks the release of FSH and LH in women Fluoxymesterone ( Halotestin ) Hypogonadism; breast cancer Testolactone ( Teslac ) Breast cancers
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Copyright  ©  2008 Lippincott Williams & Wilkins. Androgens Actions Increase the retention of nitrogen, sodium, potassium  Decrease the urinary excretion of calcium Increase protein anabolism  Decrease protein catabolism  Increase the production of red blood cells Indications Replacement therapy in hypogonadism and delayed puberty  in males Inoperable breast cancer Prevention of ovulation to treat endometriosis
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