NTR 500-1-Protein metabolism

NTR 500-1-Protein metabolism - Proteinmetabolism Concepts...

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Protein metabolism
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Concepts 1- Amino acid pool 2- Protein turnover       300-400 gm/day 3- Protein degradation     a) Ubiquitin-proteosome               (energy, endogenous )      b) Lysosomal               (no energy, exogenous)
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Ubiquitin-proteasome   degradation
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Protein digestion
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Protein digestion
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Protein digestion,cont. 1- Stomach:      a) HCl (pH 2-3)      b) Pepsin (endopeptidase)           Pepsinogen-------> pepsin  (need pepsin and  HCl)                  Protein-------> Peptides + amino acids 2- Small intestine       a) Pancreatic enzymes              (trypsin, chymotrypsin, elastase and caboxypeptidase  )         
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Pancreatic enzymes, cont.   *The enzymes are released as zymogens  by the action of CCK and secretin:     Trypsinogen   Trypsin (activates other             enzymes) as follows :
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This note was uploaded on 02/21/2011 for the course NTR 503 taught by Professor Dr.lisa during the Spring '10 term at SUNY Buffalo.

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NTR 500-1-Protein metabolism - Proteinmetabolism Concepts...

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