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Topic 04-Metabolism-S_2011

Topic 04-Metabolism-S_2011 - PGY452/552 Human Physiology...

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PGY452/552: Human Physiology: Endocrinology A. Click to edit Master subtitle style 4. Quick view of metabolism A. Food to energy B. 3 basic foods & in 4 organs C. Metabolic pathways D. Integration of metabolism
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Why bother with metabolism? Common view of metabolism Not relevant to complex organisms Does not account for Specialized roles of 22 Metabolic control is a major function of the endocrine system
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Most energy in is stored FOOD C a r b o h y d r a t e s F a t s Basil Metaboli sm Involunt ary moveme nt Voluntar y moveme nt Excess Short-term storage: carbohydrate s Short & long- term storage: fats Growth & Developm ent Energy in Energy out Heat P r o t e i n s 33
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Energy out = 2300 kcal/day Basal metabolic rate (BMR) Minimum expenditure ~1400 kcal/day° 1 kcal/min CNS important consumer BMR . 60% of energy out Thermogenesis = heat production Movement 70 kg (150 pounds) Movement is the major source of variability of energy out 44
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Metabolism=storage & use of carbohydrates & fats Anabolism Catabolism Fatty acids Amino acids Glycogen Proteins Triacylglycerols Storage Usage ENERGY Glucos e 55
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