Topic 11-Epinephrine-S_2011

Topic 11-Epinephrine-S_2011 - 11. Epinephrine & the...

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Click to edit Master subtitle style 11. Epinephrine & the fast stress response A. The adrenal medulla B. Synthesis of epinephrine C. Control D. The diversity of adrenergic receptors
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2 The adrenal medulla secretes catecholamines n Catecholamines q Epinephrine (adrenal hormone) q Norepinephrine (CNS) n Synthesized in Adrenal Medulla q Granule Cells q Specialized sympathetic ganglion Sympathe synapses granul es Medulla C Circulation
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33 The adrenal medulla is an extension of the autonomic nervous system n Hypothalamus/pituitary CNS & endocrine system n Adrenal medulla T sympathetic nervous system & endocrine system n FAST endocrine stress response Hypothala mus Preganglionic sympathetic nerve Spinal cord Adrenal medulla Acetylchol ine Epinephri ne Chromafin cell
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44 Epinephrine secreted in response to n Stress perception ¤ CNS n Down spinal cord to sympathetic nerve n Acetylcholine (ACh) is § Trauma § Pain § Anxiety § Hypoglycem ia § Hypothermi a § Hypovolemi a Spinal  cord Acetylcholine Epinephri ne Sympatheti c nerve
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55 O H C H 2 C H N H 2 HO OC Tyrosin e O H C H 2 C H N H 2 H O H Dopami ne O H C H C H 2 H N O H H O C H 3 Epinephri ne O H C H 2 C H N H 2 HO OC O H DOPA Tyrosine hydroxylas e Dopamine - β hydroxylase Amino acid decarboxylas e Phenyl ethanolamine- N - methyltransfera n
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Topic 11-Epinephrine-S_2011 - 11. Epinephrine & the...

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