lecture_26legge - Exam 3 Review Exam III Review 11/19/2009...

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1 Exam III Review 11/19/2009 Exam 3 Review Chapters: 12 Enzyme Kinetic Mechanisms 8 Carbohydrates 14 Metabolism 15 Glucose Metabolism 16 Glycogen Metabolism and Gluconeogenesis 17 Primarily pyruvate dehydrogenase. The Citric acid cycle It is called the Krebs cycle or the tricarboxylic and is the “hub” of the metabolic system. It accounts for the majority of carbohydrate, fatty acid and amino acid oxidation It also accounts for a majority of the oxidation. It also accounts for a majority of the generation of these compounds and others as well. Amphibolic - acts both catabolically and anabolically 3NAD+ + FAD + GDP + Pi + acetyl-CoA 3NADH + FADH 2 + GTP + CoA + 2CO 2 The citric acid cycle enzymes are found in the matrix of the mitochondria Substrates have to flow across the outer and inner parts of the mitochondria
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2 Nathan Kaplan and Fritz Lipmann discovered Coenzyme A and Ochoa and Lynen showed that acetyl- CoA was intermediate from pyruvate to citrate. The five reactions of the pyruvate dehydrogenase multi enzyme complex CoA acts as a carrier of acetyl groups
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lecture_26legge - Exam 3 Review Exam III Review 11/19/2009...

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