Biochemistry

Biochemistry - Chem 1004 - Spring 2011 Biochemistry...

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1 Biochemistry Chemistry of living things and life processes. Cell: structural unit of all living organisms. Cells are specific to the function of the particular tissue. Parts of the cell: Chemical composition, structure and function. Biomolecules • Phospholipids • Proteins • Carbohydrates • Lipids (fats and oils) • Nucleic acids Blackboard: http://blackboard.gwu.edu OfFce Hours: MW 3:10-3:55 PM, 1957 E street, room 113 or by appointment Chem 1004 - Spring 2011 Basic structure Phospholipids Constituents of cell membranes Simplified representation of a phospholipid molecule: Cell membrane Cell membrane
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2 Examples of amino acids Proteins Side chain: combination of C,H, and sometimes O, N, or S determines the identity of the amino acid The __________________________ determines the function of the protein. All natural proteins are formed from the combination of only 20 different amino acids alanine serine phenylalanine Class of protein Example Function of example structural proteins collagen connective tissue (tendons) enzymes DNA polymerase replicates and repairs DNA transport proteins hemoglobin transports O 2 to the cells contractile proteins actin, myosin cause contraction of muscles hormones insulin regulates glucose metabolism toxins snake venoms incapacitate food animals protective proteins antibodies complex with foreign proteins Examples of Protein Functions Formation of a peptide bond (condensation reaction) Simpli±ed representation of a protein aa 1 aa 2 aa 3 aa 4 aa 5 aa n Protein structure Primary structure : Secondary structure : aa 1 aa 2 aa 3 aa 4 aa 5 aa n
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3 Tertiary structure : Quaternary structure : Protein structure
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Biochemistry - Chem 1004 - Spring 2011 Biochemistry...

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