Note (3ì›”9)

Note (3ì›”9) - Fat as an energy source: Fat...

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Fat as an energy source: - Fat (lipid) contains energy in chemical bonds that can be used to perform many different kinds of work - Which lipids that can be oxidized (broken down) to produce ATP? o Fatty acids (also called free fratty acids or FFA) 16 carbon fatty acid (most common in human metabolism) is called palmitate - Fatty acids are stored in plants and animals (including humans) as triglycerides - Very energy dense molecules = 9 kcal/gram Where is fat stored? - Adipose tissue (cells called adipocytes) - Subcutaneous (under the skin) fat is main storage - Visceral fat is mainly in the abdomen around the vital organs and is strongly related to heart disease, diabetes, etc. Large-Volume liposuction - Removed fat (9kg in normal subjects; 11kg in subjects w/Type 2 DM) but no change in energy balance - No change in blood cholesterol or insulin or any other markers for disease To use the energy stored in fat: 1. Mobilization - Exercise causes release of stress hormone (eg epinephrine, also called adrenaline
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Note (3ì›”9) - Fat as an energy source: Fat...

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