{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

Bioinformatic identification of FGF, p38-MAPK, and calcium signalling pathways

Bioinformatic identification of FGF, p38-MAPK, and calcium signalling pathways

Info icon This preview shows pages 1–4. Sign up to view the full content.

View Full Document Right Arrow Icon
This Provisional PDF corresponds to the article as it appeared upon acceptance. Fully formatted PDF and full text (HTML) versions will be made available soon. Bioinformatic identification of FGF, p38-MAPK, and calcium signalling pathways associated with carcinoma in situ in the urinary bladder BMC Cancer 2008, 8 :37 doi:10.1186/1471-2407-8-37 Malene Herbsleb ([email protected]) Ole F Christensen ([email protected]) Thomas Thykjaer ([email protected]) Carsten Wiuf ([email protected]) Michael Borre ([email protected]) Torben F Orntoft ([email protected]) Lars Dyrskjot ([email protected]) ISSN 1471-2407 Article type Research article Submission date 24 August 2007 Acceptance date 31 January 2008 Publication date 31 January 2008 Article URL http://www.biomedcentral.com/1471-2407/8/37 Like all articles in BMC journals, this peer-reviewed article was published immediately upon acceptance. It can be downloaded, printed and distributed freely for any purposes (see copyright notice below). Articles in BMC journals are listed in PubMed and archived at PubMed Central. For information about publishing your research in BMC journals or any BioMed Central journal, go to http://www.biomedcentral.com/info/authors/ BMC Cancer © 2008 Herbsleb et al. , licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0 ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Image of page 1

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
- 1 - Bioinformatic identification of FGF, p38-MAPK, and calcium signalling pathways associated with carcinoma in situ in the urinary bladder Malene Herbsleb 1 , Ole F. Christensen 2 , Thomas Thykjaer 1 , Carsten Wiuf 3 , Michael Borre 4 , Torben F. Ørntoft 1 , Lars Dyrskjøt 1 Molecular Diagnostic Laboratory, Aarhus University Hospital Skejby, Brendstrupgaardsvej 100, DK-8200 Aarhus N, Denmark 2 Dept. of Genetics and Biotechnology, Faculty of Agricultural Sciences, University of Aarhus, DK-8830 Tjele, Denmark 3 BiRC – Bioinformatic Research Center, University of Aarhus, Hoegh-Guldbergs Gade 10, Building 1090, DK-8000 Aarhus C, Denmark 4 Department of Urology, Aarhus University Hospital Skejby, Brendstrupgaardsvej 100, DK-8200 Aarhus N, Denmark § Corresponding author Email addresses: MH: [email protected] OFC: [email protected] TT: [email protected] CW: [email protected] MB: [email protected] TFØ: [email protected] LD: [email protected]
Image of page 2
- 2 - Abstract Background Carcinoma in situ (CIS) is believed to be a precursor of invasive bladder cancer. Identification of CIS is a valuable prognostic factor since radical treatment strategies can be offered these patients before the disease becomes invasive. Methods We developed a pathway based classifier approach to predict presence or absence of CIS in patients suffering from non muscle invasive bladder cancer. From Ingenuity Pathway Analysis we considered four canonical signalling pathways (p38 MAPK, FGF, Calcium, and cAMP pathways) with most coherent expression of transcription
Image of page 3

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 4
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern