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iphy 3430 1-25-11 - 1 Parasympathetic nervous system...

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1 IPHY 3430 1-25-11 REVIEW SESSION THIS THURSDAY, 7:15 Digestive System Purpose: Obtain energy-containing substrates, water, vitamins, and ions from outside body into circulation.
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2 Gastroesophageal sphincter Liver Stomach Gallbladder Pancreas Duodenum Descending colon Transverse colon Ascending colon Jejunum Cecum lleum Appendix Sigmoid colon Anus Rectum Table 16-1, pp. 582-583
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3 PURPOSE 1. Transfer energy-containing substrate, water, ions, and vitamins from outside the body into the blood Mouth 1. Mastication 2. Moisten 3. Enzymatic breakdown
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4 Formation of saliva 1. Ptyalin or α amylase 2. Mucus 3. Water 4. Thiocyanate, proteolytic enzymes, and antibodies . Salivary gland containing secretory granule. Mucus composed of glycoproteins (polysaccharides and protein) 1. Adherent qualities 2. Coats wall of gut, mouth, etc. 3. Allows particles to slide without resistance 4. Resistant to digestion 5. Can help buffer small amounts of acid Process of saliva secretion
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Unformatted text preview: 1. Parasympathetic nervous system stimulation causes release of acetylcholine (ACH) on surface of salivary gland cells. 2. ACH causes increase in membrane permeability to Ca++. 3. Ca++ causes secretory vesicles to fuse with cell membrane and break open on outer surface, emptying contents into lumen of salivary gland (exocytosis). 5 Process, cont. 4. ACH stimulation causes Na+ transport out of salivary cells by active transport (with ATP), Cl- follows passively, water moves by osmosis. 5. As water containing ions and other secretions moves toward mouth, K+ actively exchanged for Na+, HCO3- actively exchanged for Cl-. 6. Role of SNS--vary blood Fow, esp. decrease blood Fow Rates of secretion 0.5 ml per minute all the time except during sleep, when it drops below that value. Just prior to or during eating--8-10x higher than normal value Totals/day = 1-1.5 liters/day (cows = 250 liters/day)...
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