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Richards UG Neuro 11 2010

Richards UG Neuro 11 2010 - JaneE.Roberts,Ph.D...

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Jane E. Roberts, Ph.D. University of South Carolina
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Research Program Autism Fragile X Syndrome Integration of School with Clinical- Community and Experimental  Programs
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Core Symptoms Diverse spectrum Debilitating effects Increased prevalence
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ASD will encompass autism,  Pervasive Developmental  Disorder, and Aspergers. 2 Core Symptoms
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Polygenic  Epigenetic mechanisms implied Increased brain size “Disorder of Connectivity”
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http://autismspeaks.player.abacast.com/a sdvideoglossary-0.1/player/autismspeaks
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Retrospective Study & Parental Report: 50% of infants <12 months display symptoms 80% of toddlers <24 months display symptoms Median age at initial diagnosis is 4.0 years Median age of diagnosis is 5.7 years despite  development of tools to diagnose at 2 years
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Extended visual fixation to objects  (Zwaigenbaum  et  al.,  2005) Prolonged latency to disengage visual  attention  (Bryson et al., 2004; Ozonoff et al., 2008; Zwaigenbaum et al., 2005) Marked passivity and decreased activity  levels in first year with change to increased  negative affect, lower positive affect, and  difficulty controlling attention on temperament  scales  ( Brian et al., 2008; Garon et al., 2009; Zwaigenbaum  et al ., 2005) Sensory oriented behaviors including  reactivity to visual and auditory stimuli  ( Simmons et 
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What are the challenges to early detection  of ASD?
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