RMP1222010bb - n i.e. the membrane is more permeable to K+...

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Anatomy
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What is the difference between a nucleus and a ganglion? Location, both are collections of cell bodies. One in CNS and one outside n How many Lamina are found in the cortex? 6
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Keys to … Neurons specialized for electrical activity Convert electrical to chemical signal at synapse
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What is the most critical factor in the neurons ability to communicate?
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Lipid Bilayer FAT Barrier Compartmentalized ION Channels Semipermeable Selectively leaky
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Polarized –difference in charge across membrane Neuronal membrane is semi permeable K+ channels always open Diffusion Concentration Gradient Electrical gradient/ Electrostatic pressure Opposites attract
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A balance of electrical and chemical forces Anions Cations
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Hodgkin and Katz n Squid giant axon Altered extra membrane K+ K+ is key source of Resting membrane potential
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Unformatted text preview: n i.e. the membrane is more permeable to K+ than any other ion. n Greater concentration of K+ inside than out So What Happens along the membrane to maintain the RMP? At Rest K+ Enters (Electrostatic pressure) Leaves ( Concentration Gradient) Equilibrium NO NET FLUX OF POTENTIAL RMP -70 mV Na+ - K+ pump Ion Channel Na+ K+ K+ INSIDE THE NEURON -70 mV The Action Potential Hodgkin and Katz o Remember K+ is major contributor to maintaining RMP the membrane is more permeable to K+ than any other ion. n Greater concentration of K+ inside than out But what about the action potential? Na+ little effect on resting membrane potential n Increased permeability during rise and overshoot of AP...
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RMP1222010bb - n i.e. the membrane is more permeable to K+...

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