Molecular Evolution

Molecular Evolution - How do these timelines explain why...

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
Bio 201 Molecular Evolution I. Nature of Evolution at the DNA level a. How much polymorphism do we tend to see among DNA sequences? b. What similar pattern do we see when we compare 2 sequences from the same population vs. 2 sequences from different populations (or species)? c. Understand the processes of: i. Positive selection acting on beneficial mutations ii. Purifying selection acting on deleterious mutations iii. Genetic Drift acting on neutral mutations d. Consider hypothetical timelines that describe the fixation process for new mutations in each of these processes.
Background image of page 1
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: How do these timelines explain why most polymorphism results from neutral mutations? e. What is the difference between polymorphism and divergence? II. The Molecular Clock a. How do we calculate Genetic Distance? b. How do we use genetic distance to describe ancestral evolutionary relationships? c. How do we use genetic distance together with the fossil record to get a picture of the Molecular Clock? d. Why do we say that divergence occurs according to a Molecular Clock? e. How did we use the Molecular Clock to time the Origin of HIV in humans?...
View Full Document

This note was uploaded on 02/24/2011 for the course BIOL 201 taught by Professor Mitchell during the Spring '07 term at UNC.

Ask a homework question - tutors are online