Cell Biology D103

Cell Biology D103 - Lec 1 Why should we study bio? o...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon
Lec 1 - Why should we study bio? o Provide insight into mechanism of how the cells work o Essential for the understanding of human diseases and their treatment - Approaches to understanding biology o Cell biology Reveals size, shape and location of cellular components Provides insight into mechanism o Biochemistry: Reveals molecular structure and chemistry of purified cell constituents o Genetics: Reveals roles of healthy genes and the consequences of damaged genes o Developmental Biology: Reveals changes in cells as they specialize - Comparing the size of biological objects o Atoms (smallest) o Small molecules, i.e. glucose o Macromolecules, i.e. hemoglobin o Assemblies, i.e. ribosomes o Cells, i.e. bacterium, red blood cells o Multicellular organism, i.e. c. elegans - Limitations of microscopy o Rule of thumb for the resolving power of microscope: ½ wavelength o Wavelength between 700 to 400nm - Electron microscope o Can resolve structures as small as .2nm o Electrons which have a much shorter wavelength serve as a light source - Info obtained by microscopy o Microscopy allows to determine how something looks (size, number) o where something localizes o Microscopy does NOT provide information about the function of a structure or protein the concentration of a protein the mechanism of how a process works - Model systems o 3 types of systems Prokaryotic Single cell eukaryote Multicellular organism o The simplest possible organism that alls a scientist to address a particular question The choice of the model system depends on the particular question of research
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Lec 2 Biological Membranes 1. the lipid bilayer and its characteristics 2. membrane proteins - What is the function of a membrane o Separate inside from outside (permeability) o Allow molecule exchange with the environment (selectively permeability) o Allow communication with its environment (flexible-fluid) - Fluid mosaic model of biological membranes o Lipids assemble into bilayers in which proteins form the active components of signal transduction and transport - Lipids are amphiphatic o Polar (hydrophilic) head o Non-polar (hydrophobic) tails o Membrane lipids differ in Head group Length of hydrophobic tail Degree of saturation of the hydrophobic tail Backbone (glycerol or sphingosine) - What is cholesterol? o
Background image of page 2
Image of page 3
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 02/25/2011 for the course BIO SCI D103 taught by Professor Suetterlin/macgregor during the Winter '08 term at UC Irvine.

Page1 / 6

Cell Biology D103 - Lec 1 Why should we study bio? o...

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online