Module 35: HungerThe Physiology of HungerPhysiological determinants of hunger…Glucose: the form of sugar that circulates in the blood and provides the major source of energy for body tissues.- if the glucose level drops, hunger increasesTwo hypothalamic centers help control eating…1. Lateral hypothalamus (sides) – when electrically stimulated, well-fed animals eat, when destroyed, they have no intereset in food.-Orexin: Hunger-triggering hormone secreted by hypothalamus2. Ventromedial hypothalamus (lower-mid) – depresses hunger. Stimulation makes an animal stop eating, destroying it makes the stomach and intestines process food more rapidly, causing it to become very fat.Ghrelin: hormone secreted by empty stomach; sends “I’m hungry” signals to brain.Leptin: protein secreted by fat cells; when abundant, causes brain to increase metabolism and decrease hunger.PYY: Digestive tract hormone; sends “I’m not hungry” signals to brain.
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