caffeineextraction

caffeineextraction - Extraction of Caffeine from NoDoz...

Info iconThis preview shows pages 1–4. Sign up to view the full content.

View Full Document Right Arrow Icon
Joe Julian CH:221:12 Tuesday, 1-4 PM September 21, 2004 Extraction of Caffeine from NoDoz Tablets and Assessment of Purity Via TLC
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
2 Abstract Caffeine is an alkaloid stimulant that is used to increase alertness. It is present in analgesics and in some stimulants. In this experiment, caffeine was extracted from NoDoz tablets and was purified through the process of sublimation. A percent yield of 70% was acquired for the extraction of caffeine from the tablets and a percent recovery of 44% was obtained during sublimation. By using TLC, the purities of crude, sublimated, and pure caffeine were compared and little difference was found between them. The yields for this experiment were sufficient, but could have been improved with increased care when executing the methods. Introduction Caffeine is an alkaloid stimulant that is found in the cacao plant and was discovered to be present in coffee in 1820 1 . Its stimulating effects also make it an effective compound in treating pain when used in conjunction with analgesics 1 . It is also found to increase activity in the central nervous center, thereby increasing alertness 1 . Moderate doses of caffeine, which is considered to be about 300mg daily, can increase alertness without adverse side effects 2 . In this experiment, the extraction of caffeine from NoDoz tablets was attempted. The goal was to acquire as much caffeine as was listed to be in the tablet. Purification of the caffeine was achieved through sublimation. The purity of the sublimated caffeine was compared via TLC to the purity of the crude caffeine extracted and from a sample of pure caffeine. Figure 1. The structure of caffeine.
Background image of page 2
3 Experimental Procedure Two NoDoz tablets were ground with a mortar and pestle and transferred to a 250mL Erlenmeyer flask that contained a boiling stone. To the flask, 80mL of water was added and the mixture was boiled on a hot plate for 10 minutes 3 . The mixture was cooled to room temperature and decanted into a 250mL Erlenmeyer flask. The solution was poured into a 125mL separatory funnel and extracted with 2 x 15mL of dichloromethane. The dichloromethane solution was collected in a 125mL Erlenmeyer flask. Anhydrous sodium sulfate was added to the solution until it stopped clumping. The dried solution was decanted into a tared 100mL round-bottom flask containing a boiling stone. The flask was connected to a vacuum adapter and the solvent
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 4
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 02/26/2011 for the course CHEM 2423 taught by Professor Houstonbrown during the Spring '11 term at Cy-Fair College.

Page1 / 9

caffeineextraction - Extraction of Caffeine from NoDoz...

This preview shows document pages 1 - 4. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online